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The effects last because grapefruit-mediated inhibition of drug metabolizing enzymes, like CYP3A4, is irreversible; [30] that is, once the grapefruit has "broken" the enzyme, the intestinal cells must produce more of the enzyme to restore their capacity to metabolize drugs that the enzyme is used to metabolize. [19]
Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to ...
The least healthy fruit of all of the powerhouse fruits is the white grapefruit, according to the CDC. It scored 10.47 on the agency's ranking, compared to a perfect 100 for watercress .
Grapefruit is famously juicy and tangy, with its yellow, pink or ruby flesh reaching peak ripeness in the winter months. The citrus gets a lot of buzz during cold and flu season and weight-loss ...
Grapefruit growing in the grape-like clusters from which their name may derive. The evergreen grapefruit trees usually grow to around 4.5–6 m (15–20 ft) tall, although they may reach 13.7 m (45 ft). [1] The leaves are up to 15 cm (6 in) long, thin, glossy, and dark green. They produce 5 cm (2 in) white flowers with four or five petals.
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
Congenital iodine deficiency syndrome (CIDS), also called cretinism, [2] is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone production (hypothyroidism) often caused by insufficient dietary iodine during pregnancy.