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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Most of these medications are benzimidazole derivatives, related to omeprazole, but imidazopyridine derivatives such as tenatoprazole have also been developed. [77] Potassium-competitive inhibitors such as revaprazan reversibly block the potassium-binding site of the proton pump, acting more quickly, but are not available in most countries.

  3. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    Omeprazole was a subject of a patent litigation in the U.S. [66] The invention involved application of two different coatings to a drug in pill form to ensure that the omeprazole did not disintegrate before reaching its intended site of action in stomach. Although the solution by means of two coating was obvious, the patent was found valid ...

  4. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]

  5. Bisphosphonate - Wikipedia

    en.wikipedia.org/wiki/Bisphosphonate

    The uses of bisphosphonates include the prevention and treatment of osteoporosis, Paget's disease of bone, bone metastasis (with or without hypercalcemia), multiple myeloma, primary hyperparathyroidism, osteogenesis imperfecta, fibrous dysplasia, and other conditions that exhibit bone fragility.

  6. Medication-related osteonecrosis of the jaw - Wikipedia

    en.wikipedia.org/wiki/Medication-related_osteo...

    Exposed and necrotic bone or a fistula that probes to bone in patients with pain, infection, and one or more of the following: exposed and necrotic bone extending beyond the region of alveolar bone (i.e., inferior border and ramus in the mandible, maxillary sinus and zygoma in the maxilla) resulting in pathologic fracture, extra-oral fistula ...

  7. The best sleep masks of 2025, according to sleep scientists - AOL

    www.aol.com/lifestyle/best-sleep-masks-195532296...

    Saatva's weighted eye mask takes a two-pronged approach to improving sleep — blocking light and deep pressure stimulation. At $75, this one could also make our list as the best luxury sleep mask ...

  8. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Omeprazole; Use of NSAIDs as part of dental management of patients with vascular disease should be discouraged as NSAIDs have antiplatelet effect. Instead, simple analgesics such as paracetamol or co-codamol should be of first choice. If NSAIDs are required, the risk of bleeding increases with duration of dental treatment. [3]

  9. This breakfast food might prevent colon cancer

    www.aol.com/news/breakfast-food-might-prevent...

    So if a person really does not like yogurt, they "can eat such healthy foods, such as whole grains and dietary fiber, instead," he said. Original article source: This breakfast food might prevent ...

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