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A review article in U.S. Pharmacist in 2013 states that long-term use of PPIs is associated with decreased calcium absorption (causing increased risk of osteoporosis and fractures), decreased magnesium absorption (causing electrolyte disturbances), and increased risk of certain infections such as C. difficile and community-acquired pneumonia ...
The risk of having osteoporosis includes age and sex. Risk factors include both nonmodifiable (for example, age and some medications that may be necessary to treat a different condition) and modifiable (for example, alcohol use, smoking, vitamin deficiency). In addition, osteoporosis is a recognized complication of specific diseases and disorders.
Osteoporosis and bone fracture have been observed in people on high-dose and/or long-term (over one year) prescription proton pump inhibitors. [ 21 ] Hypomagnesia has been observed in people on medications like pantoprazole when taken for longer periods of time (generally one year or more, although cases have been reported with regimens as ...
Over the past couple of months we've discussed many of the biggest risk factors associated with some of the leading causes of death in the United States -- heart disease, cancer and stroke. Today ...
Osteoporosis impacts almost 20% of women and 5% of men ages 50 and up, according to the Centers for Disease Control and Prevention, making it a concern for many. Now, a study suggests that working ...
In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported more frequently with omeprazole. This may be due to its longer availability and, hence, clinical experience.
Effectiveness is similar to other proton pump inhibitors (PPIs). [8] It is taken by mouth. [6] Common side effects include constipation, feeling weak, and throat inflammation. [6] Serious side effects may include osteoporosis, low blood magnesium, Clostridioides difficile infection, and pneumonia. [6] Use in pregnancy and breastfeeding is of ...
Its effectiveness is similar to that of other PPIs. [6] It is taken by mouth. [4] Onset is over a few hours and effects last up to a couple of days. [4] Common side effects include constipation, abdominal pain, and nausea. [4] [3] Serious side effects may include osteoporosis, low blood magnesium, Clostridioides difficile infection, and pneumonia.