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During this time, the single-layered paramesonephric duct epithelium differentiates into other structures, ranging from the ciliated columnar epithelium in the uterine tube to stratified squamous epithelium in the vagina. [8] The paramesonephric ducts and the mesonephric ducts share a majority of the same mesenchyme due to Hox gene expression.
The internal genitalia consist of two accessory ducts: mesonephric ducts (male) and paramesonephric ducts (female). The mesonephric system is the precursor to the male genitalia and the paramesonephric to the female reproductive system. [8] As development proceeds, one of the pairs of ducts develops while the other regresses.
In the female, the paramesonephric ducts persist and undergo further development. The portions which lie in the genital cord [citation needed] fuse to form the uterus and vagina. This fusion of the paramesonephric ducts begins in the third month, and the septum formed by their fused medial walls disappears from below upward.
Female Male Gonad: Ovary: Testicle: Rete ovarii: Rete testis: Paramesonephric ducts (Müllerian ducts) Fallopian tube: Appendix testis: Uterus, cervix, vagina [1] Prostatic utricle: Mesonephric ducts (Wolffian ducts) Epoophoron: Epididymis: Gartner's duct: Vas deferens: Seminal vesicle: Mesonephric tubules: Paroophoron: Paradidymis: Urogenital ...
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Paramesonephric ducts are paired ducts derived from the embryo, and for females develop into the uterus, uterine tubes, cervix and upper two-thirds of the vagina. [6] Embryogenesis of the Müllerian ducts play important roles in ensuring normal development of the female reproductive tract.
It is located in the developing fetus between the orifices of the mesonephric ducts on the urogenital sinus. [1] The uterovaginal primoridium, which is a fusion of the caudal ends of paramesonephric ducts, contacts the dorsal wall of the urogenital sinus and, induces the formation of the sinus tubercle. This occurs in both sexes:
It has been suggested that embryos with a higher expression of Dmrt1 expression develop into males while embryos with a lower expression are led to female development. [ 1 ] In the mouse gonadal primordium, the genital ridge, which forms from intermediate mesoderm, becomes morphologically distinct at E10.5.