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  2. Thembi Simelane - Wikipedia

    en.wikipedia.org/wiki/Thembi_Simelane

    In 2016, Simelane as Mayor of Polokwane received a R 575 600 "loan" from a now arrested VBS fixer for a coffee shop; the loan was the only loan made out by the VBS fixer in 2016. In 2024, the Hawks raided the Polokwane Municipality offices to secure evidence of corruption related to the municipality's R349 million investment with VBS Mutual ...

  3. Cell cycle - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle

    The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.

  4. G1 phase - Wikipedia

    en.wikipedia.org/wiki/G1_phase

    G 1 phase together with the S phase and G 2 phase comprise the long growth period of the cell cycle cell division called interphase that takes place before cell division in mitosis (M phase). [1] During G 1 phase, the cell grows in size and synthesizes mRNA and protein that are required for DNA synthesis. Once the required proteins and growth ...

  5. Pre-replication complex - Wikipedia

    en.wikipedia.org/wiki/Pre-replication_complex

    Overview of chromosome duplication in the cell cycle. Assembly of the pre-replication complex only occurs during late M phase and early G1 phase of the cell cycle when cyclin-dependent kinase (CDK) activity is low. This timing and other regulatory mechanisms ensure that DNA replication will only occur once per cell cycle.

  6. Cell cycle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle_checkpoint

    In eukaryotes, the cell cycle consists of four main stages: G 1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G 2, during which cell growth continues and the cell synthesizes various proteins in preparation for division; and the M phase, during which the duplicated ...

  7. Neuronal cell cycle - Wikipedia

    en.wikipedia.org/wiki/Neuronal_cell_cycle

    The Neuronal cell cycle represents the life cycle of the biological cell, its creation, reproduction and eventual death. The process by which cells divide into two daughter cells is called mitosis . Once these cells are formed they enter G1, the phase in which many of the proteins needed to replicate DNA are made.

  8. Spindle apparatus - Wikipedia

    en.wikipedia.org/wiki/Spindle_apparatus

    In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. It is referred to as the mitotic spindle during mitosis , a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis , a process ...

  9. Cell division - Wikipedia

    en.wikipedia.org/wiki/Cell_division

    The different stages of mitosis all together define the M phase of an animal cell cycle—the division of the mother cell into two genetically identical daughter cells. [3] To ensure proper progression through the cell cycle, DNA damage is detected and repaired at various checkpoints throughout the cycle.