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Panadol night is a GlaxoSmithKline painkiller intended for use at night. It consists of 500 milligrams of paracetamol , 25 milligrams of diphenhydramine hydrochloride (a sedating antihistamine) and other "non-hazardous ingredients" [ 1 ] It is sold in Australia , Cyprus , United Kingdom , Ireland , New Zealand and the Middle East .
For many over 65, a night of undisturbed sleep is not an option. The causes are varied, including menopause and sleep apnea. See what might keep you up.
Paracetamol's bioavailability is dose-dependent: it increases from 63 % for 500 mg dose to 89 % for 1000 mg dose. [6] Its plasma terminal elimination half-life is 1.9–2.5 hours, [ 6 ] and volume of distribution is roughly 50 L. [ 132 ] Protein binding is negligible, except under the conditions of overdose, when it may reach 15–21 %. [ 6 ]
Sleep problems in women can manifest at various stages of their life cycle, as supported by both subjective and objective data. [further explanation needed] Factors such as hormonal changes, aging, psycho-social aspects, physical and psychological conditions and the presence of sleeping disorders can disrupt women's sleep.
Addiction to prescription painkillers among seniors is growing in America, and there are specific drugs that are more harmful than others.
It is sold over-the-counter in Canada and the United States; [17] [19] in the United Kingdom, it is a prescription-only medication. [15] In Australia and the European Union, it is indicated for difficulty sleeping in people over the age of 54. [23] [8] In the European Union, it is indicated for the treatment of insomnia in children and ...
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