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Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition (1:1,000,000), in which the bones have lesions, inflammation, and pain. It is called multifocal because it can appear in different parts of the body, primarily bones, and osteomyelitis because it is very similar to that disease, although CRMO appears to be without any infection .
Osteomyelitis (OM) is an infection of bone. [1] Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. [1] The feet, spine, and hips are the most commonly involved bones in adults. [2] The cause is usually a bacterial infection, [1] [7] [2] but rarely can be a fungal infection. [8]
Vertebral osteomyelitis is a type of osteomyelitis (infection and inflammation of the bone and bone marrow) that affects the vertebrae. It is a rare bone infection concentrated in the vertebral column. [2] Cases of vertebral osteomyelitis are so rare that they constitute only 2%-4% of all bone infections. [3]
A Brodie abscess is a subacute osteomyelitis, appearing as an accumulation of pus in bone, frequently with an insidious onset. [1] Brodie's abscess is characterized by pain and swelling without fever, often resulting from diabetic wounds, fracture-related bone infection, or haematogenous osteomyelitis.
Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, [1] is a very rare skeletal condition of unknown cause.It is characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.
An entity initially known as chronic recurrent multifocal osteomyelitis was first described in 1972. [1] Subsequently, in 1978, [2] several cases of were associated with blisters on the palms and soles (palmoplantar pustulosis).
Rarely, large anterior cervical spine osteophytes may affect the esophagus or the larynx and cause pain, difficulty swallowing [5] [6] or even dyspnea. [7] Similar calcification and ossification may be seen at peripheral entheseal sites, including the shoulder, iliac crest , ischial tuberosity , trochanters of the hip, tibial tuberosities ...
According to a 2008 study, the incidence of discitis in the United States is around 0.4 to 2.4 per 100,000 people each year depending on age group. [5] According to a later 2016 study, the combined prevalence of discitis and vertebral osteomyelitis with or without spinal epidural abscess for persons under 20 years old is uncommon (0.3 per 100,000 persons), and higher in older patients (6.5 per ...