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CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast , Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [ 28 ] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied.
Male_Masturbation_with_Ejaculation_Video.webm (WebM audio/video file, VP8/Vorbis, length 1 min 15 s, 720 × 480 pixels, 851 kbps overall, file size: 7.6 MB) This is a file from the Wikimedia Commons .
The one biomarker that has been in use over the last 20 years is CA-125. [121] A 2016 review found that this biomarker was present in those with symptoms of endometriosis; and, once ovarian cancer has been ruled out, a positive CA-125 may confirm the diagnosis. [122] Its performance in ruling out endometriosis is low. [122]
Iodine-125 (125 I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging and in radiation therapy as brachytherapy to treat a number of conditions, including prostate cancer, uveal melanomas, and brain tumors. It is the second longest-lived radioisotope of iodine, after iodine-129.
48,XXYY syndrome is a condition related to the X and Y chromosomes (the sex chromosomes). People normally have 46 chromosomes in each cell.Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics.
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Simufilam (PTI-125) is an experimental medication for the treatment of Alzheimer's disease. [ 2 ] [ 3 ] It was being developed by the American pharmaceutical firm Cassava Sciences . Development of simufilam was discontinued in November 2024 after it failed to show clinical benefit during phase III clinical trials .
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