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A vestibulectomy is a gynecological surgical procedure that can be used to treat vulvar pain, specifically in cases of provoked vestibulodynia. Vestibulodynia (vulvar vestibulitis) is a chronic pain syndrome that is a subtype of localized vulvodynia [1] where chronic pain and irritation is present in the vulval vestibule, which is near the entrance of the vagina. [2]
"7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, [1] [2] excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always ...
Provoked vestibulodynia, pain provoked by contact localized to the vulvar vestibule, is the most common subtype of vulvodynia among premenopausal women. [2] The condition has been cited as affecting about 10% to 15% of women seeking gynecological care. [3]
Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Vulvodynia is a chronic pain condition that affects the vulvar area and occurs without an identifiable cause. [1] Symptoms typically include a feeling of burning or irritation. [ 2 ] It has been established by the ISSVD that for the diagnosis to be made symptoms must last at least three months.
Vulvar cancer accounts for about 5% of all gynecological cancers and typically affects women in later life. Five-year survival rates in the United States are around 70%. [1] ...
Lidocaine's half-life in the body is about 1.5–2 hours. [2] The time it takes for the anesthetic medication to prevent pain in the area (speed of onset) and length of time that the area does not have painful sensations are considerations when choosing an appropriate approach to dental treatment.
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...