Search results
Results from the WOW.Com Content Network
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
Endocrine disrupting chemicals (EDCs) are sneaky substances found in everyday items like plastics, pesticides, and even personal care products. They can mimic or interfere with your natural ...
Endocrine disruptors are exogenous substances that act like hormones in the endocrine system and disrupt the physiologic function of endogenous hormones. They are sometimes also referred to as hormonally active agents , endocrine disrupting chemicals , or endocrine disrupting compounds .
In this way, xenohormones act as endocrine disruptors by increasing or decreasing the activation of hormone receptors in the body. Xenohormones can often act on multiple hormone receptor types and enact multiple different effects. For example, BPA acts as an agonist of estrogen receptors and as an antagonist of androgen receptors. [15]
For premium support please call: 800-290-4726 more ways to reach us
Although research on endocrine disruptors or "obesogens" is still emerging, the public health implications so far have mainly surrounded obesity, diabetes, and cardiovascular disease. Obesity has become a pandemic, increasing for all population groups. From 1980 to 2008, the rates of obesity have doubled for adults and tripled for children. [47]
The principal examples are hypothalamic-pituitary hormones that can be classified from several viewpoints: they are hypothalamic hormones (originating in the hypothalamus), they are hypophysiotropic hormones (affecting the hypophysis, that is, the pituitary gland), and they are tropic hormones (having other endocrine glands as their target).
BPA is an example of an endocrine disruptor which negatively affects reproductive development by acting as an estrogen mimicker (xenoestrogen) and a likely androgen mimicker. [46] Bisphenol A exposure in fetal female rats leads to mammary gland morphogenesis , increased formation of ovarian tumors , and increased risk of developing mammary ...