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Berdazimer sodium, sold under the brand name Zelsuvmi, is a medication used for the treatment for molluscum contagiosum. [1] Berdazimer sodium is a nitric oxide releasing agent. [1] It is a polymer formed from sodium 1-hydroxy-3-methyl-3-(3-(trimethoxysilyl)propyl)-1-triazene-2-oxide and tetraethyl silicate. [3]
Berdazimer sodium, sold under the brand name Zelsuvmi, is a medication used for the treatment for molluscum contagiosum. [28] Berdazimer sodium is a nitric oxide releasing agent. [28] It is a polymer formed from sodium 1-hydroxy-3-methyl-3-(3-(trimethoxysilyl)propyl)-1-triazene-2-oxide and tetraethyl silicate. [29]
It is used for the treatment of human papillomavirus (HPV) infections with external warts as well as molluscum contagiosum infections. [11] 0.5% PPT cream is prescribed for twice daily applications for 3 days followed by 4 days with no application; this weekly cycle is repeated for four weeks. [12]
Imiquimod has been tested for treatment of molluscum contagiosum. Two large randomized controlled trials, however, found no evidence of effectiveness of imiquimod in treating children with molluscum contagiosum, and concerning adverse effects were also noted. [25] These disprove earlier anecdotal claims and smaller, less reliable studies.
[a] Its main current use in pharmacology is treating molluscum contagiosum and warts topically. [2] It is a burn agent and poisonous in large doses, and has been historically used as aphrodisiacs (Spanish fly). In its natural form, cantharidin is secreted by the male blister beetle, and given to the female as a copulatory gift during mating.
The Molluscum contagiosum virus virion is described as oval-shaped and has the dimension of approximately 320 nm × 250 nm × 200 nm. The virus has two distinct infectious particles called the mature virion (MV) and the enveloped virion (EV), which differ in that the EV contains a second outer cellular membrane.
Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of enteroviruses. [10] It typically begins with a fever and feeling generally unwell. [10] This is followed a day or two later by flat discolored spots or bumps that may blister, on the hands, feet and mouth and occasionally buttocks and groin.
A 2013 review suggested probiotics are effective in treating persistent diarrhea in children, though more research is needed. Persistent diarrhea is an episode that starts acutely but then lasts for 14 days or more; In developing countries it is an important cause of morbidity and mortality in children under five years old. The study showed ...
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