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Patients are typically given one or two 100,000 I.U. vials of ulinastatin (reconstituted in 100 ml of dextrose 5% or 100 ml of 0.9% normal saline) by intravenous infusion over the course of one hour, one to three times per day for three to five days. The dosage may be adjusted according to patients' age and the severity of symptoms.
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
For venous insufficiency, the dosage is 2 tablets of 500mg daily. For acute hemorrhoidal attack, the dosage is 6 tablets daily for 4 days, followed by 4 tablets daily over the next 3 days. [15] For chronic venous disease, the dosage is 2 tablets a day for at least 2 months. [16]
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A UK study showed that methenamine is as effective as daily low-dose antibiotics at preventing UTIs among women who experience recurrent UTIs. As methenamine is an antiseptic, it may avoid the issue of antibiotic resistance. [16] [17] Methenamine acts as an over-the-counter antiperspirant due to the astringent property of formaldehyde. [18]
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