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English: Depiction of the various key subsets of CD4-positive T cells with corresponding associated cytokines and transcription factors. Figure legend T cells leave the thymus in a naïve, antigen non-experiened state. After contact with antigen, T cells may take on one of numerous subsets.
Lymphocyte: B cell: MBC; 8-10 Memorizes the characteristics of the antigens; Triggers an accelerated and robust secondary immune response [4] [16] Killer T cell: Lymphocyte: T cell: T lymphocyte; Lymphocytus T; 8-10 Virus-infected cells; Cancer cells; Recruits and communicates with other types of immune cells [4] [17] Memory T cell: Lymphocyte ...
Download as PDF; Printable version; In other projects ... Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. [1]
At this point chronic inflammation ensues, and functional CD4 + T cell levels begin to decrease, eventually to a point where the CD4 + T cell population is too small to recognize the full range of antigens that could potentially be detected. The depletion of CD4 T cells and the development of chronic inflammation are signature processes in HIV ...
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...
In COVID-19 B cell, natural killer cell, and total lymphocyte counts decline, but both CD4 + and CD8 + cells decline to a far greater extent. [12] Low CD4 + predicted greater likelihood of intensive care unit admission, and CD4 + cell count was the only parameter that predicted length of time for viral RNA clearance.
The coordinated expression of these specific transcription factors activate or repress target genes critical in the differentiation of the lymphocyte subsets. [27] In particular, Nfil3, whose expression is regulated by cytokines, controls the differentiation of ILCs via the transcription factors Id2, RORγt, Eomes, and Tox . [ 29 ]
ILC3 cells produce cytokines typical for the population of Th17 helper lymphocytes. The characteristic feature of ILC3 is the expression of the RORγt transcription factor, which is needed for its development and expression of the chemokine receptor CCR6. [2] This group of ILC produces IL-17 (especially IL-17A) [4] and IL-22. [5]