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  2. Immune thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/.../Immune_thrombocytopenic_purpura

    Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes.

  3. Thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Thrombocytopenia

    Oral petechiae/purpura - immune thrombocytopenic purpura. Many cases of immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura, can be left untreated, and spontaneous remission (especially in children) is not uncommon. However, counts under 50,000/μL are usually monitored with regular blood tests, and those ...

  4. Thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Thrombocytopenic_purpura

    By tradition, the term idiopathic thrombocytopenic purpura is used when the cause is idiopathic, or unknown. However, most cases are now considered to be immune-mediated. [citation needed] Another form is thrombotic thrombocytopenic purpura. [citation needed]

  5. Immune-mediated thrombocytopaenia - Wikipedia

    en.wikipedia.org/wiki/Immune-mediated...

    Common symptoms of IMT include lethargy, anorexia, pyrexia, haemorrhage, and bruising. [1] Destruction of platelets occurs when immunoglobins attach to the surface of the platelet, which causes macrophages to initiate phagocytosis. [2] IMT is differentiated from other forms of thrombocytopaenia by the immune-mediated component of the condition. [3]

  6. Thrombotic thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Thrombotic...

    Thrombotic thrombocytopenic purpura (TTP) initially presents with a range of symptoms that may include severe thrombocytopenia (platelet count usually < 30,000/mm³), microangiopathic hemolytic anemia (evidenced by schistocytes in the blood smear), and various clinical signs such as petechiae, purpura, neurologic symptoms, myocardial ischemia ...

  7. Evans syndrome - Wikipedia

    en.wikipedia.org/wiki/Evans_syndrome

    Immune thrombocytopenic purpura is a condition in which platelets are destroyed by an autoimmune process. Platelets are a component of blood that contribute to the formation of blood clots in the body to prevent bleeding. The syndrome was first described in 1951 by R. S. Evans and colleagues. [1]

  8. Common variable immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Common_variable...

    The most common autoimmune disorders observed in CVID are autoimmune cytopenia, idiopathic thrombocytopenic purpura (ITP), AIHA and neutropenia. Furthermore, autoimmune endocrinological ( insulin-dependent diabetes , autoimmune thyroiditis ), gastrointestinal (anemia, autoimmune enteropathy), dermatological ( psoriasis , vitiligo ) and ...

  9. Thrombotic microangiopathy - Wikipedia

    en.wikipedia.org/wiki/Thrombotic_microangiopathy

    The second category of TMAs is TTP thrombotic thrombocytopenic purpura, which can be divided into 3 categories: congenital, idiopathic, and non-idiopathic. [5] Congenital and idiopathic TTP are generally associated with deficiencies in ADAMTS13, a zinc metalloprotease responsible for cleaving Very Large vWF Multimers in order to prevent ...

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