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IUBMB Life is the flagship journal of the International Union of Biochemistry and Molecular Biology and is devoted to the rapid publication of the most novel and significant original research articles, reviews, and hypotheses in the broadly defined fields of biochemistry, molecular biology, cell biology, and molecular medicine.
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What was the molecular mechanism that allows the association of the amino acids with their triplet codons? [1] What were the biochemical paths from individual bio-building blocks like amino acids or nucleic acids to functional polymers such as proteins and DNA?
Progress in Biophysics and Molecular Biology is a peer-reviewed scientific journal publishing review articles in the fields of biophysics and molecular biology. It was established in 1950 as Progress in Biophysics and Biophysical Chemistry , obtaining its current title in 1963.
The primary disadvantage of in vitro experimental studies is that it may be challenging to extrapolate from the results of in vitro work back to the biology of the intact organism. Investigators doing in vitro work must be careful to avoid over-interpretation of their results, which can lead to erroneous conclusions about organismal and systems ...
Molecular biology is the study of the molecular underpinnings of the biological phenomena, focusing on molecular synthesis, modification, mechanisms and interactions. Biochemistry is the study of the chemical substances and vital processes occurring in living organisms .
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment.
One of the first model systems for molecular biology was the bacterium Escherichia coli (E. coli), a common constituent of the human digestive system. The mouse ( Mus musculus ) has been used extensively as a model organism and is associated with many important biological discoveries of the 20th and 21st centuries. [ 39 ]