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AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors. [1] [2] [3] [4]
The Society for Clinical Trials (SCT) is an American professional organization in Philadelphia, Pennsylvania dedicated to advancing the science and practice of clinical trials. Established in 1978, SCT is an international organization with a membership of hundreds of individuals from academia, industry, government, and non-profit organizations.
As a result of pressure from HIV-infected men in the gay community, [citation needed] who demanded better access to clinical trials, the U.S. Congress passed the Health Omnibus Programs Extension Act of 1988 (Public Law 100-607) [2] which mandated the development of a database of AIDS Clinical Trials Information Services (ACTIS). [3]
[18] [17] [15] As of 2023, MD Anderson Cancer Center is home to the highest number of cancer clinical trials in the world and has received more NCI-funded projects than any other U.S. institute. [19] [20] For 2024, Newsweek placed MD Anderson at #1 in their annual list of the World's Best Specialized Hospitals in oncology. [21]
The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]
The public side of EudraCT is for organisations to register any of their clinical trials as defined by Directive 2001/20/EC.The process of applying and registering a clinical trial should be completed before submitting an application to any of the Member State/s in which they anticipate running the trial.
Sarah Cannon Research Institute (SCRI) is a research organization focusing on therapies for patients which include drugs that are in development. With corporate headquarters in Nashville, Tennessee , United States, it conducts community-based clinical trials in oncology , cardiology , gastroenterology , and other therapeutic areas. [ 1 ]
It conducts clinical trials on behalf of its pharmaceutical clients to expedite the drug approval process. It is the second largest clinical research organization in the world and has helped develop approximately 95% of the 200 top-selling biopharmaceuticals on the market today. [3]
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