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D-dimer (or D dimer) is a ... D-dimer increases with age. It has therefore been suggested to use a cutoff equal to patient’s age in years × 10 μg/L ...
The onset of HLH occurs before the age of one year in approximately 70 percent of cases. ... usually low and the D-dimer level is ... a cutoff of 2400 U/mL and ...
Some items were removed, and the threshold values for the remaining items were modified to better discriminate patients even with the altered physiologic baseline of pregnancy (e.g. higher cut-off value for heart rate, lower cut-off value for age).
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Principles of D-dimer testing. Fibrin degradation products (FDPs), also known as fibrin split products, are components of the blood produced by clot degeneration. [1] Clotting, also called coagulation, at the wound site produces a mass of fibrin threads called a net that remains in place until the cut is healed. As a cut heals, the clotting ...
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In other words, a positive D-dimer is not synonymous with PE, but a negative D-dimer is, with a good degree of certainty, an indication of absence of a PE. [52] A low pretest probability is also valuable in ruling out PE. [53] The typical cut off is 500 μg/L, although this varies based on the assay. [54]
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