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  2. JNJ-26146900 - Wikipedia

    en.wikipedia.org/wiki/JNJ-26146900

    The drug is a nonsteroidal androgen receptor (AR) modulator with mixed agonistic and antagonistic (antiandrogenic) effects. [2] [6] In animals, it partially prevents castration-induced loss of body weight, lean body mass (LBM), and bone and reduces prostate weight and prostate tumor growth.

  3. Medical uses of bicalutamide - Wikipedia

    en.wikipedia.org/wiki/Medical_uses_of_bicalutamide

    Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...

  4. Leuprorelin - Wikipedia

    en.wikipedia.org/wiki/Leuprorelin

    Lupron injection was approved by the FDA for treatment of advanced prostate cancer on 9 April 1985. [ 45 ] [ 4 ] [ 43 ] [ 44 ] Lupron depot for monthly intramuscular injection was approved by the FDA for palliative treatment of advanced prostate cancer on 26 January 1989.

  5. Androgen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Androgen_deprivation_therapy

    Androgen deprivation therapy (ADT), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer. Prostate cancer cells usually require androgen hormones, such as testosterone, to grow. ADT reduces the levels of androgen hormones, with drugs or surgery, to prevent ...

  6. Can Cancer in Dogs Be Treated With Ivermectin? - AOL

    www.aol.com/cancer-dogs-treated-ivermectin...

    There is no indication that a dog with this type of cancer could avoid surgery. If the tumor is small and can be removed completely, the dog will have a much better prognosis. If surgery is not an ...

  7. Comparison of bicalutamide with other antiandrogens

    en.wikipedia.org/wiki/Comparison_of_bicalutamide...

    A 2015 Cochrane review found that NSAA monotherapy for prostate cancer had a greater risk of treatment discontinuation due to adverse effects than monotherapy with a GnRH agonist or surgical castration (RR = 1.82). [122] This included a greatly increased risk of breast pain (RR = 22.97) and gynecomastia (RR = 8.43). [122]

  8. Column: Pharmacy middlemen claim to keep prescription prices ...

    www.aol.com/news/column-pharmacy-middlemen-claim...

    The FTC report offers two case studies involving generic cancer drugs in which the agency says PBMs reimbursed their affiliated pharmacies more for prescriptions than unaffiliated pharmacies ...

  9. Management of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Management_of_prostate_cancer

    For men over 64 with prostate cancer limited to the pelvis, using fewer, larger doses of radiation (hypofractionation) results in similar overall survival rates. [28] The risk of dying from prostate cancer or having acute bladder side effects may be similar to that of longer radiation treatment. [28]

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