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As benzene is ubiquitous in gasoline and hydrocarbon fuels that are in use everywhere, human exposure to benzene is a global health problem. Benzene targets the liver, kidney, lung, heart and brain and can cause DNA strand breaks and chromosomal damage, hence is teratogenic and mutagenic .
Hippuric acid has long been used as an indicator of toluene exposure; [14] however, there appears to be some doubt about its validity. [15] There is significant endogenous hippuric acid production by humans; which shows inter- and intra-individual variation influenced by factors such as diet, medical treatment, alcohol consumption, etc. [15] This suggests that hippuric acid may be an ...
DDT and DDE are resistant to metabolism; in humans, their half-lives are 6 and up to 10 years, respectively. In the United States, these chemicals were detected in almost all human blood samples tested by the Centers for Disease Control in 2005, though their levels have sharply declined since most uses were banned. [84]
Long-term exposure — meaning a year or more —to benzene can cause “harmful effects on the bone marrow and can cause a decrease in red blood cells, leading to anemia,” according to the CDC ...
Benzene is a known cancer-causing chemical that is widely used across the U.S. to make plastic and synthetic fibers, according to the CDC. ... In some studies of the effects on humans, it was ...
Despite varying levels of toxicity amongst different variants of oil, all petroleum -derived products have adverse impacts on human health and the ecosystem. Examples of adverse effects are oil emulsions in digestive systems in certain mammals might result in decreased ability to digest nutrients that might lead to death of certain mammals.
1,4-Benzoquinone is a toxic metabolite found in human blood and can be used to track exposure to benzene or mixtures containing benzene and benzene compounds, such as petrol. [25] The compound can interfere with cellular respiration, and kidney damage has been found in animals receiving severe exposure.
The most sensitive effects are caused at body burdens relatively close to those reported in humans. Among the animals for which TCDD toxicity has been studied, there is strong evidence for the following effects: Birth defects (teratogenicity) In rodents, including rats, [46] mice, [47] hamsters and guinea pigs, [48] birds, [49] and fish. [50]
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