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  2. Periorbital dark circles - Wikipedia

    en.wikipedia.org/wiki/Periorbital_dark_circles

    The lack of nutrients in the diet, or the lack of a balanced diet, can contribute to the discoloration of the area under the eyes. It is believed that iron deficiency and vitamin B 12 deficiency can cause dark circles as well. [7] Iron deficiency is the most common type of anemia and this condition is a sign that not enough oxygen is getting to ...

  3. Xerophthalmia - Wikipedia

    en.wikipedia.org/wiki/Xerophthalmia

    It may be caused by vitamin A deficiency, [1] which is sometimes used to describe that condition, although there may be other causes. Xerophthalmia caused by a severe vitamin A deficiency is described by pathologic dryness of the conjunctiva and cornea. The conjunctiva becomes dry, thick and wrinkled. The first symptom is poor vision at night.

  4. Bitot's spots - Wikipedia

    en.wikipedia.org/wiki/Bitot's_spots

    A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)

  5. Keratomalacia - Wikipedia

    en.wikipedia.org/wiki/Keratomalacia

    Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva ). The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body.

  6. Pernicious anemia - Wikipedia

    en.wikipedia.org/wiki/Pernicious_anemia

    Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]

  7. List of systemic diseases with ocular manifestations - Wikipedia

    en.wikipedia.org/wiki/List_of_systemic_diseases...

    There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.

  8. Toxic and nutritional optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_and_nutritional...

    The predominant cause of nutritional optic neuropathy is thought to be deficiency of B-complex vitamins, particularly thiamine [2] (vitamin B 1), cyanocobalamin (vitamin B 12) and recently copper. [3] Deficiency of pyridoxine (vitamin B 6), niacin (vitamin B 3), riboflavin (vitamin B 2), and/or folic acid also seems to play a role. Those ...

  9. Color blindness - Wikipedia

    en.wikipedia.org/wiki/Color_blindness

    Vitamin A deficiency may also cause color blindness. [47] Color blindness may be a side effect of prescription drug use. For example, red–green color blindness can be caused by ethambutol, a drug used in the treatment of tuberculosis. [48] Blue–yellow color blindness can be caused by sildenafil, an active component of Viagra. [49]