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  2. Periorbital dark circles - Wikipedia

    en.wikipedia.org/wiki/Periorbital_dark_circles

    The lack of nutrients in the diet, or the lack of a balanced diet, can contribute to the discoloration of the area under the eyes. It is believed that iron deficiency and vitamin B 12 deficiency can cause dark circles as well. [7] Iron deficiency is the most common type of anemia and this condition is a sign that not enough oxygen is getting to ...

  3. Toxic and nutritional optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_and_nutritional...

    The predominant cause of nutritional optic neuropathy is thought to be deficiency of B-complex vitamins, particularly thiamine [2] (vitamin B 1), cyanocobalamin (vitamin B 12) and recently copper. [3] Deficiency of pyridoxine (vitamin B 6), niacin (vitamin B 3), riboflavin (vitamin B 2), and/or folic acid also seems to play a role. Those ...

  4. Mitochondrial optic neuropathies - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_optic...

    Of the acquired category, disease falls into further etiological distinction as arising from toxic (drugs or chemicals) or nutritional/metabolic (vitamin deficiency/diabetes) insult. It is worth mentioning that under-nutrition and toxic insult can occur simultaneously, so a third category may be understood as having a combined or mixed etiology.

  5. Periorbital hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Periorbital_hyperpigmentation

    Periorbital hyperpigmentation, also known as hereditary dark circles, is characterized by darker skin around the eyes caused by the presence of additional melanin. It is an extremely common hereditary human characteristic and is frequently found on individuals with dark skin. Periorbital hyperpigmentation is most prevalent within the 16–25 ...

  6. Keratomalacia - Wikipedia

    en.wikipedia.org/wiki/Keratomalacia

    Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva).. The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body.

  7. Bitot's spots - Wikipedia

    en.wikipedia.org/wiki/Bitot's_spots

    A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)

  8. List of systemic diseases with ocular manifestations - Wikipedia

    en.wikipedia.org/wiki/List_of_systemic_diseases...

    There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.

  9. Xerophthalmia - Wikipedia

    en.wikipedia.org/wiki/Xerophthalmia

    It may be caused by vitamin A deficiency, [1] which is sometimes used to describe that condition, although there may be other causes. Xerophthalmia caused by a severe vitamin A deficiency is described by pathologic dryness of the conjunctiva and cornea. The conjunctiva becomes dry, thick and wrinkled. The first symptom is poor vision at night.

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