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  2. High-grade prostatic intraepithelial neoplasia - Wikipedia

    en.wikipedia.org/wiki/High-grade_prostatic...

    There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer. It tends to occur in the peripheral zone of the prostate.

  3. Gleason grading system - Wikipedia

    en.wikipedia.org/wiki/Gleason_grading_system

    The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...

  4. Prostate cancer staging - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_staging

    For prostate cancer, cell morphology is graded based on the Gleason grading system. [ citation needed ] Of note, this system of describing tumors as "well-", "moderately-", and "poorly-" differentiated based on Gleason score of 2–4, 5–6, and 7–10, respectively, persists in SEER and other databases but is generally outdated.

  5. Grading (tumors) - Wikipedia

    en.wikipedia.org/wiki/Grading_(tumors)

    Of the many cancer-specific schemes, the Gleason system, [3] named after Donald Floyd Gleason, used to grade the adenocarcinoma cells in prostate cancer is the most famous. This system uses a grading score ranging from 2 to 10. Lower Gleason scores describe well-differentiated less aggressive tumors.

  6. New Urine Test for Prostate Cancer May Help Reduce ...

    www.aol.com/lifestyle/urine-test-prostate-cancer...

    Researchers found that the test had a 95% sensitivity for prostate cancer of grade group 2 or greater, and 99% for grade group 3 or greater. “It does look impressive and exciting.

  7. Management of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Management_of_prostate_cancer

    However, a recent retrospective study suggests that men under 60 with high grade prostate cancer have higher survival rates with surgery than with beam radiation. [32] Rates for impotence when comparing radiation to nerve-sparing surgery are similar.

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