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2. Modified-release dosage - Wikipedia

   en.wikipedia.org/wiki/Modified-release_dosage

   Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...

3. Melatonin as a medication and supplement - Wikipedia

   en.wikipedia.org/wiki/Melatonin_as_a_medication...

   Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]

4. Stimuli-responsive drug delivery systems - Wikipedia

   en.wikipedia.org/wiki/Stimuli-responsive_drug...

   The highly targeted and controlled release ability, as well as their broad applications, make pH-responsive drug delivery systems some of the most well-researched and sought after clinical solutions in stimuli-responsive drug delivery. [3]

5. Melatonin - Wikipedia

   en.wikipedia.org/wiki/Melatonin

   Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

6. Osmotic-controlled release oral delivery system - Wikipedia

   en.wikipedia.org/wiki/Osmotic-controlled_Release...

   Merck & Co. later developed the Controlled-Porosity Osmotic Pump (CPOP) with the intention of addressing some of the issues that led to Osmosin's withdrawal via a new approach to the final stage of the release mechanism. [1] Unlike the EOP, the CPOP had no pre-formed hole in the outer shell for the drug to be expelled out of.

7. Study Says Melatonin May Help Repair DNA as You Sleep - AOL

   www.aol.com/study-says-melatonin-may-help...

   For example, a 2017 study of 30 popular melatonin supplements found that the amount of melatonin in the bottle didn't match what the label said. The researchers also found that 26 percent of the ...