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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Sleep deprivation, which often happens in the third trimester of pregnancy and the postpartum period, is a common seizure trigger (particularly for frontal lobe and idiopathic generalized epilepsy seizures). Pregnant women with epilepsy should collaborate with their healthcare providers and support system to develop a comprehensive sleep plan ...
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
The EU Cosmetics Directive defines in Annex VIIIa the language-neutral open-jar symbol, which manufacturers should use to indicate this period. The time period is most often represented compactly as a number of months, followed by the letter "M", as in "36M" or "36 M" for a period of thirty-six months, written either onto the front side of the ...
99. Da'Saahn Brame (No. 5 TE), signs with Tennessee. 100. Noah Mikhail (No. 7 LB), Texas A&M commit. Early signing period: Team rankings 2025 class. This section will be updated live as class ...
When you're a kid, there's really no time early enough to open your presents on Christmas morning. But it turns out that opening your presents before breakfast apparently makes you seem "vulgar ...
Costco ran pre-Black Friday sales in early November, trying to dodge a hit to sales in the first quarter ended Nov. 24 this year, from the late Thanksgiving weekend, which extended into December.
People with epilepsy can have healthy pregnancies and healthy babies. However, proper planning and care is essential to minimize the risk of congenital malformations or adverse neurocognitive outcomes for the fetus while maintaining seizure control for the pregnant person with epilepsy.
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