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  2. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Decongestants are often used in conjunction with cold medications or to combat pregnancy rhinitis in pregnant women. Common decongestants include pseudoephedrine and phenylephrine . [ 14 ] Pseudoephedrine is an alpha-adrenergic receptor agonist that enacts a vasoconstrictive effect to reduce airflow resistance in the nasal cavity and allow ...

  3. Chiral drugs - Wikipedia

    en.wikipedia.org/wiki/Chiral_drugs

    The drug was withdrawn from world market when it became evident that the use in pregnancy causes phocomelia (clinical conditions where babies are born with deformed hand and limbs). Later in late 1970s studies indicated that the (R)- enantiomer is an effective sedative , the (S)-enantiomer harbors teratogenic effect and causes fetal abnormalities.

  4. Anticonvulsant - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant

    Use of anticonvulsant medications should be carefully monitored during use in pregnancy. [94] For example, since the first trimester is the most susceptible period for fetal development, planning a routine antiepileptic drug dose that is safer for the first trimester could be beneficial to prevent pregnancy complications. [95]

  5. Opioids and pregnancy - Wikipedia

    en.wikipedia.org/wiki/Opioids_and_pregnancy

    Opioid drugs are used for various reasons during pregnancy, with pain being a frequent issue. Conditions like pelvic and lower back pain, occurring in around 68 to 72% of pregnancies, are commonly treated with these medications. [2] [3] [4] Moreover, other sources of pain like muscle aches, migraines, and joint pain are commonly reported during ...

  6. Thalidomide scandal - Wikipedia

    en.wikipedia.org/wiki/Thalidomide_scandal

    Thalidomide brought on changes in the way drugs are tested, what type of drugs are used during pregnancy, and increased the awareness of potential side effects of drugs. According to Canadian news magazine programme W5, most, but not all, victims of thalidomide receive annual benefits as compensation from the Government of Canada. Excluded are ...

  7. Zidovudine - Wikipedia

    en.wikipedia.org/wiki/Zidovudine

    It can be used by mouth or by slow injection into a vein. [6] Common side effects include headaches, fever, and nausea. [6] Serious side effects include liver problems, muscle damage, and high blood lactate levels. [6] It is commonly used in pregnancy and appears to be safe for the fetus. [6]

  8. Battle over pregnancy drug highlights risks of FDA expediting ...

    www.aol.com/news/battle-over-pregnancy-drug...

    The years-long effort to yank the drug's approval offers a case study of the agency's accelerated approval program, which green-lit Makena in 2011.

  9. Hydroxycarbamide - Wikipedia

    en.wikipedia.org/wiki/Hydroxycarbamide

    Use during pregnancy is typically harmful to the fetus. [4] Hydroxycarbamide is in the antineoplastic family of medications. It is believed to work by blocking the making of DNA. [4] Hydroxycarbamide was approved for medical use in the United States in 1967. [4] It is on the World Health Organization's List of Essential Medicines. [6]