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  2. Regular and irregular antibodies - Wikipedia

    en.wikipedia.org/wiki/Regular_and_irregular...

    Regular and irregular antibodies are two main groups of antibodies when classified roughly on the timing and triggering event of antibody production.. Regular antibodies usually refer to the isohemagglutinins, directed against antigens of the ABO system.

  3. IgG deficiency - Wikipedia

    en.wikipedia.org/wiki/IgG_deficiency

    IgG deficiency is a form of dysgammaglobulinemia where the proportional levels of the IgG isotype are reduced relative to other immunoglobulin isotypes.. IgG deficiency is often found in children as transient hypogammaglobulinemia of infancy, which may occur with or without additional decreases in IgA or IgM.

  4. Immunoglobulin therapy - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_therapy

    Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin) to treat several health conditions. [13] [14] These conditions include primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain–Barré syndrome, and certain other infections when a ...

  5. Dysgammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Dysgammaglobulinemia

    IgG deficiency - IgG deficiency is a lack of IgG in the absence of other immunoglobulin deficiencies. IgG levels of 300–600 mg/dL show a mild to moderate reduction of IgG while levels below 200 mg/dl are classified as a severe deficiency. [6] Those with IgG deficiency often get chronic or reoccurring pyogenic respiratory tract infections. [7]

  6. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    Methyldopa (IgG mediated type II hypersensitivity) Penicillin (high dose) Quinidine (IgM mediated activation of classical complement pathway and Membrane attack complex, MAC) (A memory device to remember that the DAT tests the RBCs and is used to test infants for haemolytic disease of the newborn is: Rh Disease; R = RBCs, D = DAT.)

  7. Antibody - Wikipedia

    en.wikipedia.org/wiki/Antibody

    Each antibody binds to a specific antigen in a highly specific interaction analogous to a lock and key.. An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that cause disease.

  8. Isotype (immunology) - Wikipedia

    en.wikipedia.org/wiki/Isotype_(immunology)

    It has the shortest half-life compared to the other IgG subclasses [11] and is frequently present together with IgG1 in response to protein antigens after viral infections. [12] IgG4 is the least abundant IgG subclass in the serum and is often generated following repeated exposure to the same antigen or during persistent infections.

  9. Immunodeficiency with hyperimmunoglobulin M - Wikipedia

    en.wikipedia.org/wiki/Immunodeficiency_with...

    Immunodeficiency with hyperimmunoglobulin M is a rare disorder characterized by recurrent infections, low or absent IgG, IgE, and IgA levels, and normal or elevated levels of IgM and IgD. [ 2 ] : 84