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The volume of distribution is 1.1 L/kg to 2.1 L/kg, but congestive heart failure can decrease it. About 60% to 80% circulates bound to the protein alpha 1 acid glycoprotein. The oral bioavailability is 35% and the topical bioavailability is 3%. Lidocaine efficacy may be reduced in tissues that are inflamed, due to competing inflammatory ...
The epinephrine causes vasoconstriction which in turn reduces systemic distribution of the anesthetic as well as prolongs its action in addition to decreasing bleeding at the operating site. Lidocaine 2% with 1:100,000 adrenaline is the local anesthetic of choice in the treatment of pregnant women. [28]
Sevoflurane is a potent vasodilator, as such it induces a dose dependent reduction in blood pressure and cardiac output.It is a bronchodilator, however, in patients with pre-existing lung pathology, it may precipitate coughing and laryngospasm.
Alphacaine or Alpha-caine is a brand name for a local anaesthetic preparation used for dental anesthesia. [1] Depending on location and manufacturer it may contain either benzocaine , articaine , or lidocaine (with or without adrenaline ).
Available in oral and injectable form, theophylline is a long-acting bronchodilator that prevents asthma episodes. It belongs to the chemical class methylxanthines (along with caffeine). It is prescribed in severe cases of asthma or those that are difficult to control. It must be taken 1–4 times daily, and doses cannot be missed.
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the front of the eyeball, the inside of the nose, ear or throat, the anus and the genital area. [1]
It is a topically applied first aid liquid with active ingredients benzalkonium chloride (an antiseptic) and lidocaine (a topical anaesthetic). As an antiseptic, Bactine can help to prevent infections, while the topical anesthetic in Bactine serves to numb the surface of a body part and temporarily relieve pain and itching on the skin. [1]
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