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Pergolide, sold under the brand name Permax and Prascend (veterinary) among others, is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease. Parkinson's disease is associated with reduced dopamine synthesis in the substantia nigra of the brain .
For example, at the 2007 Fall Yearling sale at Keeneland, 3,799 young horses sold for a total of $385,018,600, for an average of $101,347 per horse. [2] However, that average sales price reflected a variation that included at least 19 horses that sold for only $1,000 each and 34 that sold for over $1,000,000 apiece.
Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
Nearly 3 million people could receive a boost in Social Security payments under legislation set for a final Senate vote in the coming days. The Social Security Fairness Act would end longtime ...
The Mayan calendar’s 819-day cycle has confounded scholars for decades, but new research shows how it matches up to planetary cycles over a 45-year span
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Horses portal; This article is within the scope of WikiProject Equine, a collaborative effort to improve Wikipedia's coverage of articles relating to horses, asses, zebras, hybrids, equine health, equine sports, etc.
Newer synthetic ergoline derivatives that have been synthesized for the treatment of Parkinson's disease include pergolide and lisuride, which both act as dopamine agonists as well. [ 28 ] A famous ergoline derivative is the psychedelic drug LSD , a semi-synthetic ergoline alkaloid that was discovered by Albert Hofmann.