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When the test was first developed, it was pharmacologically validated through the use of benzodiazepines, a common anxiety medication. Newer drugs such as 5-HT-1A partial agonists and selective serotonin reuptake inhibitors , which have also been proven to treat anxiety, show inconsistent results in this test.
This is an accepted version of this page This is the latest accepted revision, reviewed on 16 December 2024. Order of mammals Rodent Temporal range: Late Paleocene – recent Pre๊ ๊ O S D C P T J K Pg N Capybara Springhare Golden-mantled ground squirrel North American beaver House mouse Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Class: Mammalia Mirorder ...
Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice, rats have served as an important animal model for research in psychology and biomedical science. [1]
Zapodidae, the jumping mice, is a family of mouse-like rodents in North America and China. Although mouse-like in general appearance, these rodents are distinguished by their elongated hind limbs, and, typically, by the presence of four pairs of cheek-teeth in each jaw.
In the U.S., the numbers of rats and mice used is estimated to be from 11 million [94] to between 20 and 100 million a year. [95] Other rodents commonly used are guinea pigs, hamsters, and gerbils. Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate.
Rodents have been employed in biomedical experimentation from the 1650s. [1] Currently, rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast ...
The term rat is also used in the names of other small mammals that are not true rats. Examples include the North American pack rats (aka wood rats [3]) and a number of species loosely called kangaroo rats. [3] Rats such as the bandicoot rat (Bandicota bengalensis) are murine rodents related to true rats but are not members of the genus Rattus ...
Kangaroo rats, small mostly nocturnal rodents of genus Dipodomys, are native to arid areas of western North America.The common name derives from their bipedal form. They hop in a manner similar to the much larger kangaroo, but developed this mode of locomotion independently, like several other clades of rodents (e.g. dipodids and hopping mice).