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Pepto-Bismol is an over-the-counter drug currently produced by the Procter & Gamble company in the United States, Canada and the United Kingdom. Pepto-Bismol is made in chewable tablets [ 24 ] and swallowable caplets, [ 25 ] but it is best known for its original formula, which is a thick liquid.
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
Bismuth subsalicylate (Pepto-Bismol), loperamide (Imodium), and atropine/diphenoxylate (Lomotil) are antidiarrheal agents that can be used to treat diarrhea. However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta.
It is an active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate. Other derivatives include methyl salicylate , used as a liniment to soothe joint and muscle pain, and choline salicylate , which is used topically to relieve the pain of mouth ulcers .
Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
As Keough explains in the memoir, these new drugs "only served to make her even more high because whatever the normal dose was, she would somehow get five times that amount from the doctors."
In the mid-1990s, Norwich constructed an Intermediate Potency solid dose form facility, from which the osteoporosis drug Actonel was launched. In 2001, the North Norwich plant was purchased from Procter & Gamble by Outsourcing Services Group, who revived the original Norwich Pharmaceuticals name by placing it on the sign in front of the plant ...
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