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  2. Immune-mediated thrombocytopaenia - Wikipedia

    en.wikipedia.org/wiki/Immune-mediated...

    Prednisone and prednisolone are steroids used to suppress immune response to restore platelet levels. [ 5 ] [ 8 ] [ 1 ] Side effects of these include adrenal atrophy , proteinuria and glomerular changes, weight loss, dermatitis , regurgitation , diarrhoea , gastroinestinal ulceration , hyperglycaemia , polyuria , polydipsia , decreased T4 ...

  3. Immune thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Immune_thrombocytopenic...

    Refractory ITP, which does not respond to conventional treatment or shows constant relapse after splenectomy, requires treatment to reduce the risk of significant bleeding. [3] Platelet transfusions may be used in severe cases with extremely low platelet counts in individuals experiencing bleeding.

  4. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Conditioning treatment before haematopoietic stem cell transplantation (high dose, IV), chronic myeloid leukaemia, myelofibrosis, polycythaemia vera and essential thrombocytosis Myelosuppression, seizures (high dose), tachycardia (high dose), hepatic sinusoidal obstruction syndrome (high dose), Addison-like syndrome (rare), pulmonary fibrosis ...

  5. Thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Thrombocytopenia

    One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5] Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). [6] [7]

  6. Prednisone - Wikipedia

    en.wikipedia.org/wiki/Prednisone

    Prednisone is a glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. [3] It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other steroids. [3] It is taken by mouth. [3]

  7. Thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Thrombocythemia

    High platelet counts can occur in patients with polycythemia vera (high red blood cell counts), and is an additional risk factor for complications. [ citation needed ] A very small number of people report symptoms of erythromelalgia , a burning sensation and redness of the extremities that resolves with cooling, or aspirin or both.

  8. Warm antibody autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Warm_antibody_autoimmune...

    Initial medical treatment consists of prednisone. If ineffective, splenectomy should be considered. [citation needed] If refractory to both these therapies, other options include rituximab, [4] [5] danazol, cyclosphosphamide, azathioprine, or ciclosporin. High-dose intravenous immune globulin may be effective in controlling hemolysis, but the ...

  9. Thrombotic thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Thrombotic...

    Due to the high mortality of untreated TTP, a presumptive diagnosis of TTP is made even when only microangiopathic hemolytic anemia and thrombocytopenia are seen, and therapy is started. Transfusion is contraindicated in thrombotic TTP, as it fuels the coagulopathy. Since the early 1990s, plasmapheresis has become the treatment of choice for TTP.

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