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Hepatitis A is an infectious disease of the liver caused by Hepatovirus A (HAV); [7] it is a type of viral hepatitis. [8] Many cases have few or no symptoms, especially in the young. [ 1 ] The time between infection and symptoms, in those who develop them, is two–six weeks. [ 2 ]
Fulminant hepatitis, or massive hepatic cell death, is a rare and life-threatening complication of acute hepatitis that can occur in cases of hepatitis B, D, and E, in addition to drug-induced and autoimmune hepatitis.
Hepatitis A vaccine is a vaccine that prevents hepatitis A. [2] [3] It is effective in around 95% of cases and lasts for at least twenty years and possibly a person's entire life. [4] If given, two doses are recommended beginning after the age of one. [2] It is given by injection into a muscle. [2]
The first human liver transplant was performed in 1963 by Dr. Thomas E. Starzl on a three-year-old male afflicted with biliary atresia after perfecting the technique on canine livers. [ 9 ] [ 10 ] Baruch S. Blumberg discovered hepatitis B virus in 1966 and developed the first vaccine against it 1969.
In the 1960s, the first virus that could cause hepatitis was discovered. This was hepatitis B virus, which was named after the disease it causes. [220] Hepatitis A virus was discovered in 1974. [221] The discovery of hepatitis B virus and the invention of tests to detect it have radically changed many medical, and some cosmetic procedures.
Liver transplantation is the standard of care in people presenting with fulminant liver failure or those with the progression of disease despite multiple lines of therapy. [33] [34] [35] Many patients, once started on long-term immunosuppressive therapy, will remain on that treatment for life.
Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) [2] was an African-American woman [5] whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line [B] and one of the most important cell lines in medical research.
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [1] Early symptoms can include fever, dark urine, abdominal pain, and yellow tinged skin. [1]