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When taken orally, phenylephrine has a threshold dose of about 50 mg to affect the cardiovascular system, a dose at which the drug decreases heart rate and slightly increases arterial blood pressure. [8] Additionally, an over-the-counter dose of 60 mg produces a slight increase in heart rate with no detectable changes in blood pressure. [8]
NSAIDs cause decreased ability to form blood clots, which can increase the risk of bleeding when combined with other drugs that also decrease blood clotting, such as warfarin. [113] NSAIDs may aggravate hypertension (high blood pressure) and thereby antagonize the effect of antihypertensives, [113] such as ACE inhibitors. [114]
Rarely, more severe symptoms such as gastrointestinal bleeding, seizures, metabolic acidosis, hyperkalemia, low blood pressure, slow heart rate, fast heart rate, atrial fibrillation, coma, liver dysfunction, acute kidney failure, cyanosis, respiratory depression, and cardiac arrest have been reported. [46]
Medications that can raise your blood pressure include antidepressants, birth control pills, decongestants, and non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen and aspirin. Race.
Common side effects include lightheadedness, headache, feeling tired, leg swelling, cough, and shortness of breath. [2] Serious side effects may include low blood pressure and heart failure. [2] Nifedipine is considered safe in pregnancy and breastfeeding. [5] Nifedipine was patented in 1967, and approved for use in the United States in 1981.
Beta-blockers slow the heart rate, lowering blood pressure and making the heart beat less forcefully. They’re prescribed to treat and prevent heart attacks, high blood pressure, and chest pain ...
High blood pressure (Learn more about How to Lower Blood Pressure.) High cholesterol. Heart disease. Diabetes. Obesity. Sickle cell disease. Not exercising regularly. A sedentary lifestyle ...
Antihypertensive drugs and hypertensive drugs affect blood pressure in an opposite way. [19] The most common hypertensive drugs in the UK are NSAIDs and steroids. [19] NSAIDs inhibit the synthesis of prostaglandin, which increases the blood pressure and potentially reduce the efficacy of several antihypertensive drugs. [20]