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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
An antiemetic is a drug that is effective against vomiting and nausea.Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer.
The cause of morning sickness is unknown but may relate to changing levels of estrogen and the hormone human chorionic gonadotropin. [2] [9] Some have proposed that morning sickness may be useful from an evolutionary point of view -it may protect both the pregnant woman and the developing embryo just when the fetus is most vulnerable. [1]
Due to her extreme morning sickness, Kate Middleton was recently forced to cancel a slew of engagements, which ultimately led William and Kate's official spokesperson to announce the Duchess's ...
The company focuses on women who have severe morning sickness, a condition that is seen in 14% of all pregnancies and has left women turning to Google and Reddit chats searching for answers ...
Scientists are moving forward with researching cures for morning sickness, including testing drugs that block GDF15 from binding to its receptor in the brain, and exposing women to the hormone ...
Side effects of doxylamine include dizziness, drowsiness, and dry mouth, among others. [4] Doxylamine is a potent anticholinergic and has a side-effect profile common to such drugs, including blurred vision, dry mouth, constipation, muscle incoordination, urinary retention, mental confusion, and delirium. [18] [7]
The antiemetic activity increases with increased dosing; however, side effects also increase, which often limits maximal dosing. [ 13 ] For moderate to severe morning sickness and hyperemesis gravidarum : In the UK , Promethazine is the drug of first choice.
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