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  2. Complementarity (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Complementarity_(molecular...

    A partner uses the same number of the bonds to make a complementing pair. [17] An IUPAC code that specifically excludes one of the three nucleotides can be complementary to an IUPAC code that excludes the complementary nucleotide. For instance, V (A, C or G - "not T") can be complementary to B (C, G or T - "not A").

  3. Non-canonical base pairing - Wikipedia

    en.wikipedia.org/wiki/Non-canonical_base_pairing

    Wobble base pairing occur between two nucleotides that are not Watson-Crick base pairs and was proposed by Watson in 1966. The 4 main examples are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A), and hypoxanthine-cytosine (I-C). These wobble base pairs are very important in tRNA.

  4. Base pair - Wikipedia

    en.wikipedia.org/wiki/Base_pair

    An unnatural base pair (UBP) is a designed subunit (or nucleobase) of DNA which is created in a laboratory and does not occur in nature. DNA sequences have been described which use newly created nucleobases to form a third base pair, in addition to the two base pairs found in nature, A-T (adenine – thymine) and G-C (guanine – cytosine).

  5. DNA synthesis - Wikipedia

    en.wikipedia.org/wiki/DNA_synthesis

    Each unit is joined when a covalent bond forms between its phosphate group and the pentose sugar of the next nucleotide, forming a sugar-phosphate backbone. DNA is a complementary, double stranded structure as specific base pairing (adenine and thymine, guanine and cytosine) occurs naturally when hydrogen bonds form between the nucleotide bases.

  6. Nucleic acid double helix - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_double_helix

    The DNA double helix biopolymer of nucleic acid is held together by nucleotides which base pair together. [3] In B-DNA, the most common double helical structure found in nature, the double helix is right-handed with about 10–10.5 base pairs per turn. [4] The double helix structure of DNA contains a major groove and minor groove.

  7. Nucleic acid secondary structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_secondary...

    In molecular biology, two nucleotides on opposite complementary DNA or RNA strands that are connected via hydrogen bonds are called a base pair (often abbreviated bp). In the canonical Watson-Crick base pairing, adenine (A) forms a base pair with thymine (T) and guanine (G) forms one with cytosine (C) in DNA.

  8. Nucleotide base - Wikipedia

    en.wikipedia.org/wiki/Nucleotide_base

    The viral polymerase incorporates these compounds with non-canonical bases. These compounds are activated in the cells by being converted into nucleotides; they are administered as nucleosides as charged nucleotides cannot easily cross cell membranes. [citation needed] At least one set of new base pairs has been announced as of May 2014. [15]

  9. Chargaff's rules - Wikipedia

    en.wikipedia.org/wiki/Chargaff's_rules

    A diagram of DNA base pairing, demonstrating the basis for Chargaff's rules. Chargaff's rules (given by Erwin Chargaff) state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine.