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Certain cephalosporins in dentistry can be administered orally while others can be given by injections. In the case of an allergy to penicillin, cephalosporins may be a suitable alternative. [11] [15] Metronidazole: This is an antimicrobial effective against some protozoa and strict anaerobes.
Effective for gram-positive, gram-negative, anaerobic, and against multi-antibiotic resistant bacteria (such as Staphylococcus aureus [MRSA] and Acinetobacter baumannii), but not effective for Pseudomonas spp. and Proteus spp. Teeth discoloration and same side effects as tetracycline. Not to be given to children and pregnant or lactating women.
Dental antibiotic prophylaxis is the administration of antibiotics to a dental patient for prevention of harmful consequences of bacteremia, that may be caused by invasion of the oral flora into an injured gingival or peri-apical vessel during dental treatment.
It is understood about 30-40% of cases of the rare infection infective endocarditis are caused by bacteria in the mouth.
In more severe cases, particularly deep-seated systemic infections, antibiotics can be given intravenously or by injection. [1] [35] Where the site of infection is easily accessed, antibiotics may be given topically in the form of eye drops onto the conjunctiva for conjunctivitis or ear drops for ear infections and acute cases of swimmer's ear.
Given the natural history of a mouth infection, the vast majority of clinically-treated oral infections are polymicrobial, or caused by multiple different species of bacteria at the same time. [9] Until the source of the infection is controlled with some form of drainage and antibiotics, a mouth infection will likely not resolve on its own.
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.
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