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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.
Unlike rheumatoid arthritis, lupus arthritis is less disabling and usually does not cause severe destruction of the joints. Fewer than ten percent of people with lupus arthritis will develop deformities of the hands and feet. [20] People with SLE are at particular risk of developing osteoarticular tuberculosis. [21]
Rheumatoid arthritis; A hand severely affected by rheumatoid arthritis. This degree of swelling and deformation does not typically occur with current treatment. Specialty: Rheumatology, Immunology: Symptoms: Disease course is variable: Single episode of joint inflammation followed by long last remission; Inflammation of joints over longer ...
Subacute cutaneous lupus erythematosus (SCLE ) is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as poly-cyclic annular lesions or plaques similar to those of plaque psoriasis.
The Community Research and Care Branch coordinates activities within the NIAMS Community Health Clinic, a health information resource that provides health care services to underserved populations affected by arthritis, lupus, and other rheumatic diseases. The clinic offers patient care with access to specialists, education programs, and ...
Common symptoms include extreme fatigue, joint pain or skin rashes. In rare cases, the disease may lead to kidney or heart damage, or weaken the immune system so the body can’t fight off infections.
When there is proof of an autoimmune disease, but the disease does not correspond to any specific autoimmune disease (such as systemic lupus erythematosus (SLE), scleroderma, [2] mixed connective tissue disease, Sjögren syndrome, systemic sclerosis, polymyositis, dermatomyositis, or rheumatoid arthritis), it will be
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...
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