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Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [2] and regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and luteinizing hormone (LH) work together in the ...
In the first decade of human life, there is a significant amount of overlap between children of both sexes. The gradual growth in sex difference throughout a person's life is a product of various hormones. Testosterone is the major active hormone in male development while estrogen is the dominant female hormone. These hormones are not, however ...
Male development can only occur when the fetal testis secretes key hormones at a critical period in early gestation. The testes begin to secrete three hormones that influence the male internal and external genitalia: they secrete anti-Müllerian hormone (AMH), testosterone, and dihydrotestosterone (DHT). Anti-Müllerian hormone causes the ...
In the ovary, the FSH receptor is necessary for follicular development and expressed on the granulosa cells. [5] In the male, the FSH receptor has been identified on the Sertoli cells that are critical for spermatogenesis. [12] The FSHR is expressed during the luteal phase in the secretory endometrium of the uterus. [13]
5-DHT or DHT is a male reproductive hormone that targets the prostate gland, bulbourethral gland, seminal vesicles, penis and scrotum and promotes growth/mitosis/cell maturation and differentiation. Testosterone is converted to 5-DHT by 5alpha-reductase, usually with in the target tissues of 5-DHT because of the need for high concentrations of ...
Ovulation occurs about midway through the menstrual cycle, after the follicular phase, and is followed by the luteal phase.Note that ovulation is characterized by a sharp spike in levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), resulting from the peak of estrogen levels during the follicular phase.
At this stage in development, they become dependent on hormones, particularly FSH which causes a substantial increase in their growth rate. The late tertiary or pre-ovulatory follicle ruptures and discharges the oocyte (that has become a secondary oocyte ), ending folliculogenesis.
As puberty begins and sex hormone levels rise, differences appear, though some changes are similar in males and females. Male levels of testosterone directly induce the growth of the genitals, and indirectly (via dihydrotestosterone (DHT)) the prostate. Estradiol and other hormones cause breasts to develop in females.