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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms.
Ketamine is also used to manage pain among large animals. It is the primary intravenous anesthetic agent used in equine surgery, often in conjunction with detomidine and thiopental, or sometimes guaifenesin. [173] Ketamine appears not to produce sedation or anesthesia in snails. Instead, it appears to have an excitatory effect. [174]
In 2019, the US Food and Drug Administration approved a nasal spray that uses esketamine, a cousin of ketamine, for treatment-resistant depression. The researchers on the new study say that ...
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
However, these effects are often short-lived, and attempts to prolong the antidepressant effect with repeated doses and extended ("maintenance") treatment have resulted in only modest success. [69] A nasal spray formulation of esketamine , sold under the brand name Spravato, gained FDA approval in 2019 for the treatment of treatment-resistant ...
Ketamine from the street drug trade, in the form of crystals. Ketamine, a dissociative anesthetic, has a long history of being used in clubs and was one of the most popular substances used in the New York Club Kid scene. Ketamine produces a dissociative state, characterized by a sense of detachment from one's physical body and the external ...
Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.