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"The increased levels may cause patients to experience side effects." For example, when the blood pressure drug felodipine is taken with grapefruit juice rather than water, levels of the ...
Important: If you're taking statins or medications for conditions like high blood pressure, cholesterol, heart arrhythmia, organ transplants, or allergies, it can be dangerous to eat grapefruit.
According to Harvard Health Publishing, grapefruit can be dangerous when combined with drugs used for high blood pressure, high cholesterol, and depression. Check with your doctor for guidance on ...
grapefruit juice-mediated inhibition of membrane transport proteins from the intestine to the blood, or inhibition of enzymes that activates a prodrug to an active metabolite leads to insufficient doses of the drug in the body resulting in loss of theurapeutic effect [27] Grapefruit or grapefruit juice can reduce the absorption of many drugs by ...
Grapefruit juice contains bergamottin, one of the furanocoumarins which inhibit the metabolism of many drugs, causing multiple side-effects. [21] Grapefruit and grapefruit juice interact with many drugs, resulting in numerous adverse effects including bone marrow suppression, nephrotoxicity, abnormal heart rhythm, rhabdomyolysis, hypotension ...
Block beta-1 receptors in the heart → stop the effects of catecholamines on the heart→ reduce heart rate, heart contractility and conduction velocity → reduce the workload of the heart [15] Side effects [16] Bradycardia; Hypotension; Heart Block; Impaired glucose metabolism; Central Nervous System effects: fatigue, depression, insomnia
Grapefruit is famously juicy and tangy, with its yellow, pink or ruby flesh reaching peak ripeness in the winter months. The citrus gets a lot of buzz during cold and flu season and weight-loss ...
Bitter orange may have serious grapefruit-like drug interactions with medicines such as statins (to lower cholesterol), nifedipines (to lower blood pressure), some anti-anxiety drugs, and some antihistamines. [43]