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The hypochord is a transient structure ventral to the notochord, and is primarily responsible for correct development of the dorsal aorta. [13] Notochord flexion, when the notochord bends to form a part of the developing caudal fin, is a hallmark of an early growth stage of some fish. [14] [15] [better source needed]
The notochord plays an integral role in the development of the neural tube. Prior to neurulation, during the migration of epiblastic endoderm cells towards the hypoblastic endoderm, the notochordal process opens into an arch termed the notochordal plate and attaches overlying neuroepithelium of the neural plate. The notochordal plate then ...
ventral floor of the notochordal process fuses with endoderm. The notochord will form the nucleus pulposus of intervertebral discs. There is some discussion as to whether these cells contributed from the notochord are replaced by others from the adjacent mesoderm. It gives rise to the notochordal process, which later becomes the notochord.
The prechordal cells migrate to the midline to form the notochordal plate. The chordamesoderm is the central region of trunk mesoderm. [4] This forms the notochord, which induces the formation of the neural tube, and establishes the anterior-posterior body axis. The notochord extends beneath the neural tube from the head to the tail.
From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. The lower half of one sclerotome fuses with the upper half of the adjacent one to form each vertebral body. [11]
4.1 Formation of the early nervous system – neural groove, tube and notochord. ... Diagram of stages of embryo development to a larval and adult stage.
Splits or pockets may form in the germinal sheet of cells forming vesicles or elongations. The lungs and glands of the organism may develop this way. [6] A primary step in organogenesis for chordates is the development of the notochord, which induces the formation of the neural plate, and ultimately the neural tube in
As the primitive streak continues to regress, somites form from the paraxial mesoderm by "budding off" rostrally. In certain model systems, it has been shown that the daughter cells of stem cell-like progenitor cells which come from the primitive streak or site of gastrulation migrate out and localize in the posterior paraxial mesoderm.