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Legionella is a genus of gram-negative bacteria that can be seen using a silver stain or grown in a special media that contains cysteine, an amino acid.It is known to cause legionellosis [3] (all illnesses caused by Legionella) including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. [3]
Legionella pneumophila, the primary causative agent for Legionnaire's disease, is an aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium. [1] [2] L. pneumophila is a intracellular parasite that preferentially infects soil amoebae and freshwater protozoa for replication.
Legionella spp. enter the lungs either by aspiration of contaminated water or inhalation of aerosolized contaminated water or soil. In the lung, the bacteria are consumed by macrophages, a type of white blood cell, inside of which the Legionella bacteria multiply, causing the death of the macrophage. Once the macrophage dies, the bacteria are ...
Members of the order Legionellales can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotein-releasing system transmembrane protein lolE and tRNA (guanosine(37)-N1)-methyltransferase TrmD.
L. jordanis was found to contain the gene loci sidH, sidE, sidB, and sidG which express a Dot/Icm effector protein. [13] This effector protein is essential for L. pneumophila to infiltrate host cells, so it is thought to be used as a virulence factor in L. jordanis, also. [13] Both strains of L. jordanis tested positive for proteolysis and ...
You can contract Legionnaire's disease by inhaling the bacteria (legionella), but NOT from person to person contact. Because it is a disease that affects the lungs, older adults, smokers and ...
Man-made water sources “become a health problem when small droplets of water that contain the bacteria get into the air and people breathe them in,” the CDC said in a fact-sheet. The majority ...
Almost all natural water sources contain Legionella and their presence should not be taken as an indication of a problem. The tabled figures are for total aerobic plate count, cfu/ml at 30 °C (minimum 48 hours incubation) with colony count determined by the pour plate method according to ISO 6222(21) or spread plate method on yeast extract agar.