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When high doses of aspirin are given, aspirin may actually cause hyperthermia due to the heat released from the electron transport chain, as opposed to the antipyretic action of aspirin seen with lower doses. Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of ...
Aspirin is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. [10] Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease, pericarditis, and rheumatic fever. [10]
This enables aspirin to be released directly into blood circulation, bypassing the need for absorption through the stomach as well as liver metabolism. [ 17 ] When compared to oral doses of aspirin, lysine acetylsalicylate displays a greater antiplatelet and anti-inflammatory response.
NSAIDs reduce kidney blood flow and thereby decrease the efficacy of diuretics, and inhibit the elimination of lithium and methotrexate. [ 113 ] NSAIDs cause decreased ability to form blood clots , which can increase the risk of bleeding when combined with other drugs that also decrease blood clotting, such as warfarin .
There are a few possible side effects linked to taking NSAIDs, including: gastrointestinal problems (such as irritation, ulcers, or bleeding), increased risk of heart attack and stroke, reduced ...
For adults who have survived a heart attack or stroke, taking aspirin may reduce the risk of another cardiovascular event. But a new study suggests that less than half of these cardiovascular ...
Some creams work by blocking pain signals, while others may increase blood flow or reduce inflammation. “Anesthetics, such as lidocaine, block pain signals from nerves, inducing a numbing effect ...
A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasms , pain , and hyperreflexia . The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics .
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