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The yeast has a negative effect on the bacteria that normally produce antibiotics to kill the parasite, so may affect the ants' health by allowing the parasite to spread. [41] Certain strains of some species of yeasts produce proteins called yeast killer toxins that allow them to eliminate competing strains. (See main article on killer yeast ...
The spindle pole body (SPB) is the microtubule organizing center in yeast cells, functionally equivalent to the centrosome. Unlike the centrosome the SPB does not contain centrioles. The SPB organises the microtubule cytoskeleton which plays many roles in the cell. It is important for organising the spindle and thus in cell division.
Clb5 and Clb6 are B-type, S-phase cyclins in yeast that assist in cell cycle regulation. [1] Clb5 and Clb6 bind and activate Cdk1, and high levels of these cyclins are required for entering S-phase. [2] S-phase cyclin binding to Cdk1 directly stimulates DNA replication as well as progression to the next phase of the cell cycle. [3]
Crystal Structure of the human Cdk1 homolog, Cdk2. Cdk1 is a small protein (approximately 34 kilodaltons), and is highly conserved. The human homolog of Cdk1, CDK1, shares approximately 63% amino-acid identity with its yeast homolog. Furthermore, human CDK1 is capable of rescuing fission yeast carrying a cdc2 mutation.
Many proteins important in human biology were first discovered by studying their homologs in yeast; these proteins include cell cycle proteins, signaling proteins, and protein-processing enzymes. S. cerevisiae is currently the only yeast cell known to have Berkeley bodies present, which are involved in particular secretory pathways.
Each Yip1 domain family protein contains five transmembrane domains, with the N-terminus exposed to the cytosol and the C-terminus to the Golgi apparatus lumen. [1] Yip1 domain family members are thought to interact with a partner, with two molecules of each partner forming an active tetramer complex with 20 transmembrane segments.
7514 103573 Ensembl ENSG00000082898 ENSMUSG00000020290 UniProt O14980 Q6P5F9 RefSeq (mRNA) NM_003400 NM_001035226 NM_134014 RefSeq (protein) NP_003391 NP_001030303 NP_598775 Location (UCSC) Chr 2: 61.48 – 61.54 Mb Chr 11: 23.21 – 23.25 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Exportin 1 (XPO1), also known as chromosomal region maintenance 1 (CRM1), is a eukaryotic protein ...
There are approximately 50–100 eisosomes in each mature yeast cell distributed uniformly across the cell surface periphery in a characteristic dotted pattern [2] with each eisosome containing approximately 2000–5000 copies of Pil1 [6] and Lsp1 proteins, as well as, integral membrane protein Sur7. [7]