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The isthmic organizer, or isthmus organizer, also known as the midbrain−hindbrain boundary (MHB), is a secondary organizer region that develops at the junction of the midbrain and metencephalon (embryonic hindbrain). [1] The MHB expresses signaling molecules that regulate the differentiation and patterning of the adjacent neuroepithelium.
Embryonic vertebrate subdivisions of the developing human brain hindbrain or rhombencephalon is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla , pons , and cerebellum .
The hindbrain, rhombencephalon (shaped like a rhombus) is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla , pons , and cerebellum . Together they support vital bodily processes.
The forebrain separates into two vesicles – an anterior telencephalon and a posterior diencephalon. The telencephalon gives rise to the cerebral cortex, basal ganglia, and related structures. The diencephalon gives rise to the thalamus and hypothalamus. The hindbrain also splits into two areas – the metencephalon and the myelencephalon. The ...
The midbrain links sensory, motor, and integrative components received from the hindbrain, connecting it to the forebrain. The tectum, which includes the optic tectum and torus semicircularis, receives auditory, visual, and somatosensory inputs, forming integrated maps of the sensory and visual space around the animal. [ 59 ]
Initially there are three primary brain vesicles: prosencephalon (i.e. forebrain), mesencephalon (i.e. midbrain) and rhombencephalon (i.e. hindbrain). These develop into five secondary brain vesicles – the prosencephalon is subdivided into the telencephalon and diencephalon, and the rhombencephalon into the metencephalon and myelencephalon.
The hindbrain, which is the evolutionarily most ancient part of the chordate brain, also divides into different segments called rhombomeres. The rhombomeres generate many of the most essential neural circuits needed for life, including those that control respiration and heart rate, and produce most of the cranial nerves . [ 37 ]
Brain anatomy – forebrain, midbrain, hindbrain. The cerebral peduncles each form a lobe ventrally of the tegmentum, on either side of the midline. Beyond the midbrain, between the lobes, is the interpeduncular fossa, which is a cistern filled with cerebrospinal fluid [citation needed]. The majority of each lobe constitutes the cerebral crus.