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Acid-citrate-dextrose or acid-citrate-dextrose solution, also known as anticoagulant-citrate-dextrose or anticoagulant-citrate-dextrose solution (and often styled without the hyphens between the coordinate terms, thus acid citrate dextrose or ACD) is any solution of citric acid, sodium citrate, and dextrose in water.
[1] [2] It is composed of 2.05% dextrose, 0.8% sodium citrate, 0.055% citric acid, and 0.42% sodium chloride. For usage, an equal volume of blood is gently, but thoroughly, mixed with the solution. This solution is used to study in vitro anti-inflammatory activity of crude drugs by the human red blood cell stabilization method. [3]
Potassium oxalate (anticoagulant) [6] Glucose, lactate, [7] toxicology [8] Yellow Acid-citrate-dextrose A (anticoagulant) Tissue typing, DNA studies, HIV cultures Pearlescent ("white") Separating gel and (K 2)EDTA: PCR for adenovirus, toxoplasma and HHV-6: Black Sodium Citrate: Paediatric ESR: QuantiFERON Grey, Green, Yellow, Purple QuantiFERON ...
Formulations include plain sodium citrate, acid-citrate-dextrose, and more. Oxalate has a mechanism similar to that of citrate. It is the anticoagulant used in fluoride/oxalate tubes to determine glucose and lactate levels. The fluoride inhibits glycolysis, which can throw off blood sugar measurements. Citrate/fluoride/EDTA tubes work better in ...
Three years later, the introduction by J.F. Loutit and Patrick L. Mollison of acid–citrate–dextrose (ACD) solution, which reduced the volume of anticoagulant, permitted transfusions of greater volumes of blood and allowed longer-term storage. Carl Walter and W.P. Murphy Jr. introduced the plastic bag for blood collection in 1950.
EDTA (chelator / anticoagulant) Trace elements, heavy metals, most drug levels, toxicology: Tan Sodium EDTA (chelator / anticoagulant) Lead: Gray Fluoride Oxalate. Sodium fluoride (glycolysis inhibitor) Potassium oxalate (anticoagulant) [13] Glucose, lactate, [14] toxicology [15] Yellow Acid-citrate-dextrose A (anticoagulant) Tissue typing, DNA ...
Whole blood is typically stored under the same conditions as red blood cells and can be kept up to 35 days if collected with citrate-phosphate-dextrose-adenine-1 (CPDA-1) anticoagulant solution, or 21 days with other common anticoagulants such as citrate-phosphate-dextrose (CPD). [20]
In general, tests requiring whole blood call for blood samples collected in test tubes containing some form of the anticoagulant EDTA. EDTA chelates calcium to prevent clotting. EDTA is preferred for hematology tests because it does minimum damage to cell morphology. Sodium citrate is the anticoagulant used in specimens collected for ...