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The fatty acids are then transported to the target cells but are unable to be broken down, resulting in a build-up of fatty acids in the liver and other internal organs. Fatty-acid metabolism disorders are sometimes classified with the lipid metabolism disorders, [2] but in other contexts they are considered a distinct category.
In fatty change, the cell has been damaged and is unable to adequately metabolize fat. Small vacuoles of fat accumulate and become dispersed within cytoplasm. Mild fatty change may have no effect on cell function; however, more severe fatty change can impair cellular function.
Fatty acid metabolism consists of various metabolic processes involving or closely related to fatty acids, a family of molecules classified within the lipid macronutrient category. These processes can mainly be divided into (1) catabolic processes that generate energy and (2) anabolic processes where they serve as building blocks for other ...
Others may increase calorie expenditure by boosting metabolism or limiting how much fat or carbs your body absorbs. ... a gradual calorie deficit of 500 to 750 calories a day is considered safe ...
Methylmalonic acid metabolism including some methylmalonic acidemias. In methylmalonic acidemias, the body is unable to break down properly: essential amino acids: methionine, valine, threonine and isoleucine [39] propionic acid from intestinal fermentation [39] odd-chain fatty acids [39] cholesterol side chain [39]
This process can trigger your body’s metabolism and promote autophagy—a process in which unnecessary or deteriorating cells are recycled—and accelerate lipolysis, which helps break down fat ...
Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. [ 1 ] [ 2 ] The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue .
The gut microbiota, which is a population of microbes that live in the human digestive system, also has an important part in metabolism and generally has a positive function for its host. In terms of pathophysiological/mechanism interactions, an abnormal gut microbiota can play a role in metabolic disorder related obesity .