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Once fully developed, the classic appearance is "non-blanching, palpable purpura". [6] [5] [7] This appears as deep red to purple spots that feel raised to the touch. Purpura refers to the red-purple discolored spots, while palpable implies that these spots can be felt as raised from the surrounding skin.
There are numerous causes of palpable purpura, such as autoimmune diseases, drug reactions, vaccinations, and infections.The most common infectious causes are N. gonorrhoeae, S. aureus, and N. meningitides, however palpable purpura has also been caused by Mycoplasma spp., Rickettsiae, Mycobacterium, and very rarely by Treponema pallidum, Brucella spp., Yersinia, Campylobacter, and Bartonella.
Nonthrombocytopenic purpura is a type of purpura (red or purple skin discoloration) not associated with thrombocytopenia. [1] Nonthrombocytopenic purpura has been reported after smoking mentholated cigarettes. [2] Examples/causes include: Henoch–Schönlein purpura [3] Hereditary hemorrhagic telangiectasia [4] Congenital cytomegalovirus [1 ...
Such lesions include petechia (less than 3 mm (0.12 in), resulting from numerous and diverse etiologies such as adverse reactions from medications such as warfarin, straining, asphyxiation, platelet disorders and diseases such as cytomegalovirus); [6] and purpura (3–10 mm (0.12–0.39 in)), classified as palpable purpura or non-palpable ...
Purpura (/ ˈ p ɜːr p jʊər ə / [1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [ 2 ]
IgA vasculitis (HSP), previously known as Henoch–Schönlein purpura, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain.
Palpable purpura; Panarteritis nodosa; Parkes Weber syndrome; Paroxysmal hand hematoma; Paroxysmal nocturnal hemoglobinuria; Pauci-immune; Periarteritis nodosa; Perinatal gangrene of the buttock; Pigmented purpuric dermatosis; Pigmented purpuric lichenoid dermatitis; Pigmented purpuric lichenoid dermatitis of Gougerot and Blum; Polyarteritis nodosa
Non-specific symptoms are common and include fever, headache, fatigue, myalgia, weight loss, and arthralgia. [5] [6] All forms of vasculitis, even large vessel vasculitides, may cause skin manifestations. The most common skin manifestations include purpura, nodules, livedo reticularis, skin ulcers, and purpuric urticaria. [7]
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