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Palpable purpura is the clinical manifestation of leukocytoclastic vasculitis, which can be idiopathic or linked to sepsis, reactions to drugs, connective tissue diseases, cryoglobulinemia, hepatitis C or B infection, or underlying cancers.
Once fully developed, the classic appearance is "non-blanching, palpable purpura". [6] [5] [7] This appears as deep red to purple spots that feel raised to the touch. Purpura refers to the red-purple discolored spots, while palpable implies that these spots can be felt as raised from the surrounding skin.
Purpura (/ ˈ p ɜːr p jʊər ə / [1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [ 2 ]
IgA vasculitis (HSP), previously known as Henoch–Schönlein purpura, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain.
hematuria, palpable abdominal mass, flank pain: Renal cell carcinoma: Triple Test (for diagnosis of downs syndrome) Estimation of hcg, Estriol, and AFP: Down's Syndrome: Trotter's triad: Conductive deafness, Immobility of homolateral soft palate, Trigeminal neuralgia: Nasopharyngeal carcinoma: Unhappy Triad (Also known as O'Donoghue's triad or ...
It typically presents as palpable purpura. [37] Conditions with leucocytoclasis mainly include hypersensitivity vasculitis (also called leukocytoclastic vasculitis) and cutaneous small-vessel vasculitis (also called cutaneous leukocytoclastic angiitis). An alternative to biopsy can be an angiogram (x-ray test of the blood vessels). It can ...
Clinical features may include constitutional symptoms like fever, arthralgia, myalgia, loss of appetite, weight loss and fatigue.A variety of organs can be affected, which causes a wide range of symptoms such as cough, shortness of breath, hemoptysis (coughing up of blood), symptoms of kidney failure, skin manifestations (palpable purpura and livedo racemosa [1]), seizures or peripheral ...
Immunoglobulin A (IgA) vasculitis, formerly referred to as Henoch–Schönlein purpura, is a type of immune complex vasculitis that primarily affects IgA deposits in small vessels. Acute enteritis, glomerulonephritis, arthralgias and/or arthritis, and cutaneous purpura are the most common clinical manifestations. Children are more likely than ...