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Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.
It was first identified in 1966 at the Mayo Clinic, by A.G. Engel, [2] and that same year W.K. Engel and J.S. Resnick noted another case that they elaborated in 1975. [ 3 ] [ 4 ] The diagnosis of the disease rests on subacutely evolving weakness after age 40, normal to low CK level , a myopathic EMG with fibrillations , and often a monoclonal ...
True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. Muscle weakness can also be caused by low levels of potassium and other electrolytes within muscle cells. It can be temporary or ...
A new study, led by scientists at the Mayo Clinic, Rochester, MN, may have found a possible answer. It suggests that the ability to balance on one leg is a reliable indicator of neuromuscular ...
Guillain–Barré syndrome is usually triggered by a recent infection (or more rarely a recent vaccination) and causes weakness and tingling in the arms and legs. [2] Researchers also looked at chronic inflammatory demyelinating polyneuropathy which is characterized by progressive weakness and sensory impairment in the arms and legs.
Also known as hyperthyroid myopathy, TM is one of many myopathies that lead to muscle weakness and muscle tissue breakdown. Evidence indicates the onset may be caused by hyperthyroidism . [ 1 ] Physical symptoms of TM may include muscle weakness , the breakdown of muscle tissue, fatigue , and heat intolerance . [ 2 ]
The main symptom of benign fasciculation syndrome is focal or widespread involuntary muscle activity (fasciculation). [1] The benign twitches usually have a constant location. [2] Other common symptoms are generalized fatigue or weakness, paraesthesia or numbness, and muscle cramping or spasms. [1]
Symptoms may include pain, numbness, or weakness in the arms or legs. [1] Symptoms are typically gradual in onset and improve with leaning forward. [1] Severe symptoms may include loss of bladder control, loss of bowel control, or sexual dysfunction. [1]